Piracetam is an antimyoclonic agent.
Piracetam is indicated in adult patients suffering from myoclonus of cortical origin, irrespective of etiology, and should be used in combination with other anti-myoclonic therapies.
It is formulated solution, syrup, film coated tablets for oral route of administration and injection, solution for intravenous route of administration.
Mechanism of action:
Piracetam is a positive allosteric modulator of the AMPA receptor.
It acts on ion channels or ion carriers leading to increased neuron excitability and has been found to increase blood flow glucose and oxygen consumption in parts of the brain which precedes cognitive improvement. Piracetam improves the function of the neurotransmitter acetylcholine via muscarinic cholinergic (ACh) receptors, which are implicated in memory processes. Furthermore, piracetam may have an effect on NMDA glutamate receptors, which are involved in learning and memory processes.