Ticagrelor
CAS No.
274693-27-5
Reference product
BRILINTA, BRILIQUE/AstraZeneca
Polymorphic form
Form II
Therapeutic Area
Blood & blood forming organs
Status
pipeline
EU DMF readiness
✓
US DMF readiness
028674
CEP
Pending
Other documentation
Canadian DMF
Brazilian DMF
Drug description:
Ticagrelor is an antiplatelet agent.
Ticagrelor co-administered with acetylsalicylic acid (ASA), is indicated for the prevention of atherothrombotic events in adult patients with acute coronary syndromes (ACS) or a history of myocardial infarction (MI) and a high risk of developing an atherothrombotic event.
It is formulated as tablets, film-coated tablets for oral route of administration.
Mechanism of action:
Ticagrelor is a platelet ADP P2Y12 receptor antagonist. It helps to prevent the formation of blood clots and reduces the occurrence of thrombotic events in acute coronary syndromes (ACS). ADP mediates platelet aggregation through its action on two G-protein-coupled receptor subtypes. The drug candidate is also acts by preventing adenosine from being cleared from the blood stream and by marginally increasing the levels of immune cell activity.
The above product is presented solely for informational purposes and does not constitute an offer in any sense. Products with PIPELINE & EARLY DEVELOPMENT STATUS under patent (SPC) protection in Poland and/or other countries are not offered until expiration of the corresponding IP right.