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Sodium salicylate



Reference product


Polymorphic form

Monoclinic form (space group P21/m)

Therapeutic Area

Alimentary tract & metabolism



EU DMF readiness

US DMF readiness


Other documentation

Japanese DMF

Drug description

Sodium salicylate is the sodium salt of salicylic acid. It is used as an analgesic and antipyretic.
It is also a potential replacement for aspirin for people sensitive to it.

Mechanism of action:

Sodium salicylate is a non-selective COX inhibitor. It inhibits the two isoforms of cyclooxygenase, COX-1 and COX-2. sodium salicylate irreversibly acetylates cyclooxygenases thereby inhibiting prostaglandin synthesis and associated inflammation and pain.

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