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Reference product


Polymorphic form

Form I

Therapeutic Area

Cardiovascular system



EU DMF readiness

US DMF readiness



Other documentation

Chinese DMF

💉 Available also
in injectable form

Drug description:

Pentoxifylline is a xanthine derivative belongs to vasodilator agent. It is indicated for the treatment of peripheral vascular disease, including intermittent claudication on the basis of chronic occlusive arterial disease of the limbs and for the treatment of acute arterial circulatory disorders of the eye.
It is formulated as extended release tablets for oral route of administration and as solution for injection infusion for intravenous route of administration.

Mechanism of action:

Pentoxifylline inhibits phosphodiesterase, resulting in increased levels of cyclic adenosine monophosphate (cAMP) in erythrocytes, endothelium, and the surrounding tissues. This leads to vasodilation, improves erythrocyte flexibility, and enhances blood flow. In addition, the increased level of cAMP in platelets inhibits platelet aggregation, which may contribute to a reduction in blood viscosity.

Products protected by valid patents are not offered for commercial sale in countries where the sale of such products constitutes patent infringement but are offered solely for uses reasonably related to the development and submission of information under a law regulating the manufacture, use or sale of drugs. It is within the buyer’s responsibility and liability to check the patent situation of the product in the imported market(s).