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Nefopam hydrochloride



Reference product


Polymorphic form

Therapeutic Area

Antipyretic, analgesic and anti-inflammatory



EU DMF readiness

Drug description:

Painkilling medication, primarily used to treat post-surgery moderate to severe, acute or chronic pain, also in the prevention of shivering.

Mechanism of action:

Effects in the brain and spinal cord to relieve pain via rather unique mechanisms. Firstly it increases the activity of serotonin, norepinephrine and dopamine, neurotransmitters involved in, among other things, pain signalling. Secondly it modulates sodium and calcium channels thereby inhibiting the release of glutamate, a key neurotransmitter involved in pain processing.

IPOCHEM API manufacturing site

Products protected by valid patents are not offered for commercial sale in countries where the sale of such products constitutes patent infringement but are offered solely for uses reasonably related to the development and submission of information under a law regulating the manufacture, use or sale of drugs. It is within the buyer’s responsibility and liability to check the patent situation of the product in the imported market(s).