Nefopam hydrochloride
CAS No.
23327-57-3
Reference product
Acupan
Polymorphic form
Therapeutic Area
Antipyretic, analgesic and anti-inflammatory
Status
commercial
EU DMF readiness
✓
Drug description:
Painkilling medication, primarily used to treat post-surgery moderate to severe, acute or chronic pain, also in the prevention of shivering.
Mechanism of action:
Effects in the brain and spinal cord to relieve pain via rather unique mechanisms. Firstly it increases the activity of serotonin, norepinephrine and dopamine, neurotransmitters involved in, among other things, pain signalling. Secondly it modulates sodium and calcium channels thereby inhibiting the release of glutamate, a key neurotransmitter involved in pain processing.
IPOCHEM API manufacturing site
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