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Reference product


Polymorphic form

Form II

Therapeutic Area

Cardiovascular system



EU DMF readiness

US DMF readiness


Other documentation

Korean DMF

💉 Available also
in injectable form

Drug description:

Acetazolamide belongs to the class of carbonic anhydrase inhibitors.
Acetazolamide tablets and injection indicated for the treatment of glaucoma (open angle glaucoma, secondary glaucoma, and acute angle closure glaucoma where delay of surgery is desired in order to lower intra-ocular pressure), epilepsy and also indicated for the treatment of abnormal retention of fluids in congestive heart failure and drug induced oedema.
It is formulated as powder, solution for injection for intravenous or intramuscular route of administration and tablets for oral route of administration.

Mechanism of action:

Acetazolamide is an inhibitor of carbonic anhydrase. By inhibiting the reaction catalyzed by this enzyme in the renal tubules, acetazolamide increases the excretion of bicarbonate and of cations, chiefly sodium and potassium, and so promotes alkaline diuresis. Continuous administration of acetazolamide is associated with metabolic acidosis and resultant loss of diuretic activity. Therefore, the effectiveness of Acetazolamide tablets in diuresis diminishes with continuous use. By inhibiting carbonic anhydrase in the eye, acetazolamide decreases intra-ocular pressure and is therefore useful in the treatment of glaucoma.

Products protected by valid patents are not offered for commercial sale in countries where the sale of such products constitutes patent infringement but are offered solely for uses reasonably related to the development and submission of information under a law regulating the manufacture, use or sale of drugs. It is within the buyer’s responsibility and liability to check the patent situation of the product in the imported market(s).