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Commercial
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Therapeutic Category
Alimentary tract & metabolism
Anti-infectives for systemic use
Antipyretic, analgesic and anti-inflammatory
Antineoplastic & immunomodulating agents
Blood & blood forming organs
Cardiovascular system
Genito-urinary system & sex hormones
Injectable forms
Musculo-skeletal system
Nervous system
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Piracetam

CAS No.

7491-74-9

Innovator/marketer

Nootropil

Polymorphic form

Form II

Therapeutic Area

Nervous system

Status

Commercial

EU DMF readiness

CEP

Available also in injectable form

Drug description:

Piracetam is an antimyoclonic agent.
Piracetam is indicated in adult patients suffering from myoclonus of cortical origin, irrespective of etiology, and should be used in combination with other anti-myoclonic therapies.
It is formulated solution, syrup, film coated tablets for oral route of administration and injection, solution for intravenous route of administration.

Mechanism of action:

Piracetam is a positive allosteric modulator of the AMPA receptor.
It acts on ion channels or ion carriers leading to increased neuron excitability and has been found to increase blood flow glucose and oxygen consumption in parts of the brain which precedes cognitive improvement. Piracetam improves the function of the neurotransmitter acetylcholine via muscarinic cholinergic (ACh) receptors, which are implicated in memory processes. Furthermore, piracetam may have an effect on NMDA glutamate receptors, which are involved in learning and memory processes.

DISCLAIMER
Products protected by valid patents are not offered for commercial sale in countries where the sale of such products constitutes patent infringement but are offered solely for uses reasonably related to the development and submission of information under a law regulating the manufacture, use or sale of drugs. It is within the buyer’s responsibility and liability to check the patent situation of the product in the imported market(s).

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