Aniracetam
CAS No.
72432-10-1
Reference product
N/A
Polymorphic form
Monoclinic form
Therapeutic Area
Nervous system
Status
commercial
EU DMF readiness
✓
Drug description:
Aniracetam is a psychostimulant agent.
Aniracetam is indicated for disorders of attention and memory.
It is formulated as granule for suspension and as film coated tablet for oral route of administration.
Mechanism of action:
Aniracetam stimulates the function of some glutamate receptors in the CNS, and specifically the AMPA receptor and the metabotropic receptor. The AMPA receptor plays a pivotal role in the processes of learning and memory. Intervenes, in fact, in the maintenance phase of neuronal response amplified “Long term potentiation” (LTP) which is the basis of the learning process and leads, through gene activation, protein synthesis and the formation of new synapses. Aniracetam potentiates AMPA receptor function, prolongs the duration of the maintenance phase of the curve of the amplified action potential (LTP) and supports the processes of learning. Aniracetam lacks excitatory or inhibitory type effects on the CNS direct, does not affect the activity of the autonomic nervous system and cardiovascular system.
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